Addition of Buserelin to human menopausal gonadotrophins in patients with failed stimulations for IVF or GIFT

摘要: The combined therapy of a gonadotrophin-releasing hormone agonist (GnRHa) D-Ser(TBU)6-EA10-LHRH (Buserelin) and human menopausal gonadotrophins (HMG) for ovarian stimulation in-vitro fertilization gamete intra-Fallopian transfer was evaluated during 84 cycles. All women selected this had previously failed stimulations with clomiphene citrate/HMG. GnRHa prevented spontaneous luteinizing surges premature luteinization in all patients. After addition the to HMG, cancellation rate dropped from 17 7% improved results 72.6% Twenty-six per cent started cycles resulted pregnancy. Eighteen healthy children were born at term.