Efficient oxidative N -dealkylative addition of trialkylamines to dimethyl acetylenedicarboxylate using BrCCl 3 as the terminal oxidant
作者： Fangnan Liu , Zhiguo Zhang , Zongbi Bao , Huabin Xing , Yiwen Yang
DOI: 10.1016/J.TETLET.2017.05.073
关键词:
摘要: Abstract Herein we present a continuous improvement of visible-light mediated N -dealkylative addition tertiary amines to dimethyl acetylenedicarboxylates (DMAD) using alkyl halogenides as external oxidants together with base additives. This method is highlighted by excellent tolerance various and good yields in short reaction time under mild conditions.
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