Comprehensive identification of active triterpenoid metabolites in frankincense using a coupling strategy.
作者： Yuanyan Liu , Zhenli Liu , Cheng Lu , Jianbei Li , Zhangchi Ning
DOI: 10.1016/J.JCHROMB.2014.05.054
关键词:
摘要: Abstract Frankincense resins are extensively used as natural remedies in regions ranging from North Africa to China. Triterpenoid metabolites frankincense exhibit notable anti-inflammatory and anti-tumor properties. In the present paper, without use of an isolation process, fragmentation rules NMR spectral characteristics triterpenoid summarized through a coupling method using high performance liquid chromatography-diode array detection/electrospray ionization tandem mass spectrometry (HPLC-DAD/ESI-MSn) combined with HPLC-nuclear magnetic resonance (NMR) experiments. Based on this groundwork, strategy for comprehensive metabolic profiling active enriched fractions was developed. The proposed may serve holistic screening bioactive complex TCM samples.
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