Effects of cardiomyopathy-linked mutations K15N and R21H in tropomyosin on thin-filament regulation and pointed-end dynamics.
作者： Thu Ly , Christopher T. Pappas , Dylan Johnson , William Schlecht , Mert Colpan
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摘要: Mutations K15N and R21H in striated muscle tropomyosin are linked to cardiomyopathies. It is suggested that the mutation causes cardiomyopathy by altering Ca2+-dependent thin-filament regulati...
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