Mechanical stress induces neuroendocrine and immune responses of sea cucumber (Apostichopus japonicus)

摘要: Grading procedure in routine sea cucumber hatchery production is thought to affect juvenile immunological response. The present study investigated the impact of a 3-min mechanical perturbation mimicking grading on neuroendocrine and immune parameters Apostichopus japonicus. During application stress, concentrations noradrenaline dopamine coelomic fluid increased significantly, indicating that resulted transient state stress cucumbers. Coelomocytes concentration transiently after beginning stressing, reached maximum 1 h. Whereas, coelomocytes phagocytosis at 3 min, superoxide anion from min 0.5 h, acid phosphatase activity phenoloxidase h were all significantly down-regulated. All recovered baseline levels experiment was conducted for 8 an immunostimulation occurred considering activity. results suggested that, as other marine invertebrates, neuroendocrine/immune connections exist A. Mechanical can elicit profound influence system. Neuroendocrine messengers act turn modulate immunity functions. Therefore, these effects should be considered developing better husbandry procedures.