Diabetes Mellitus and Cardiovascular Disease
作者： David S. Frankel , Peter W. F. Wilson , James B. Meigs
DOI: 10.1007/978-1-4419-5839-6_11
关键词:
摘要: Diabetes mellitus is a complex, multifactorial disorder that has an overall prevalence of about 8% in the United States. Whereas approximately 90% people with diabetes have noninsulin-dependent or type 2 (T2DM), remainder insulin-dependent 1 (T1DM). The varies greatly among different ethnic groups. Among Americans older than 20 years age, 8.7% non-Hispanic whites, 9.5% Hispanic and Latino Americans, 13.3% blacks, 15.1% American Indian Alaskan natives. These wide variations are accounted for mainly by T2DM. Although cause causes T2DM not known, environment clearly important. molecular basis T1DM better defined, but primary remains unclear. Despite etiologic pathogenic differences between T1DM, chronic sequelae both forms same; cardiovascular disease, particularly coronary heart disease (CHD), major morbidity mortality diabetic patients. In fact, CHD greater 75% deaths those shortens life expectancy 10 [1].
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