Decoding Grasping Movements from the Parieto-Frontal Reaching Circuit in the Nonhuman Primate.

摘要: Prehension movements typically include a reaching phase, guiding the hand toward object, and grip shaping around it. The dominant view posits that these components rely upon largely independent parieto-frontal circuits: dorso-medial circuit involved in dorso-lateral grasping. However, mounting evidence suggests more complex arrangement, with areas contributing to both To investigate role of grasping, we trained monkeys reach-and-grasp different objects dark determined if configurations could be decoded from functional magnetic resonance imaging (MRI) responses obtained grasping circuits. Indicative their established object-specific grasp decoding was found anterior intraparietal (AIP) area, inferior parietal lobule area PFG ventral premotor region F5 lateral circuit, primary motor cortex. Importantly, medial also conveyed robust grasp-specific information, as evidenced by significant reach regions (particular V6A) dorsal F2. These data support proposed "reach" controlling aspects demonstrate value complementing univariate sensitive multivariate analyses MRI (fMRI) uncovering information coding brain.