Magnetic resonance spectroscopy of tubers in patients with tuberous sclerosis.

摘要: Objective - The histological features of cortical tubers in patients with tuberous sclerosis (TS) were studied by the proton magnetic resonance spectroscopy (MRS). Material and methods subjects 4 children, mean age 10 years, clear evidence on MRI SPECT. Four age-matched control children served as subjects. Spectra acquired over tuber using short TE. Results myoinositol/creatine ratios TS significantly increased compared those (P < 0.02). NAA/creatine decreased Conclusions decrease was considered to reflect a reduction cranial neurons. increase thought an glial cells. Proton MRS might play role estimation changes neurological diseases.