Structural maintenance of chromosomes (SMC) proteins: conserved molecular properties for multiple biological functions.
作者： Alexander V. Strunnikov , Rolf Jessberger
DOI: 10.1046/J.1432-1327.1999.00509.X
关键词:
摘要: The evolutionarily-conserved eukaryotic SMC (structural maintenance of chromosomes) proteins are ubiquitous chromosomal components in prokaryotes and eukaryotes. form two kind heterodimers: the SMC1/SMC3 SMC2/SMC4 types. These heterodimers constitute an essential part higher order complexes, which involved chromatin DNA dynamics. most prominent best-characterized complexes cohesin condensin, necessary for sister chromatid cohesion chromosome condensation. Here we discuss these functions together with additional roles gene dosage compensation recombination.
sci-hub.se 参考文章(74)
Vincent Guacci, Douglas Koshland, Alexander Strunnikov, A Direct Link between Sister Chromatid Cohesion and Chromosome Condensation Revealed through the Analysis of MCD1 in S. cerevisiae Cell. ,vol. 91, pp. 47- 57 ,(1997) , 10.1016/S0092-8674(01)80008-8
Carrie Walowsky, David J. Fitzhugh, Irene B. Castaño, Justina Y. Ju, Nikki A. Levin, Michael F. Christman, The topoisomerase-related function gene TRF4 affects cellular sensitivity to the antitumor agent camptothecin. Journal of Biological Chemistry. ,vol. 274, pp. 7302- 7308 ,(1999) , 10.1074/JBC.274.11.7302
K. Furuya, K. Takahashi, M. Yanagida, Faithful anaphase is ensured by Mis4, a sister chromatid cohesion molecule required in S phase and not destroyed in G1 phase Genes & Development. ,vol. 12, pp. 3408- 3418 ,(1998) , 10.1101/GAD.12.21.3408
Olof Sundin, Alexander Varshavsky, Arrest of segregation leads to accumulation of highly intertwined catenated dimers: Dissection of the final stages of SV40 DNA replication Cell. ,vol. 25, pp. 659- 669 ,(1981) , 10.1016/0092-8674(81)90173-2
Francine B Perler, Protein Splicing of Inteins and Hedgehog Autoproteolysis: Structure, Function, and Evolution Cell. ,vol. 92, pp. 1- 4 ,(1998) , 10.1016/S0092-8674(00)80892-2
Aaron F. Straight, Andrew S. Belmont, Carmen C. Robinett, Andrew W. Murray, GFP tagging of budding yeast chromosomes reveals that protein–protein interactions can mediate sister chromatid cohesion Current Biology. ,vol. 6, pp. 1599- 1608 ,(1996) , 10.1016/S0960-9822(02)70783-5
R. A. Britton, D. C.-H. Lin, A. D. Grossman, Characterization of a prokaryotic SMC protein involved in chromosome partitioning Genes & Development. ,vol. 12, pp. 1254- 1259 ,(1998) , 10.1101/GAD.12.9.1254
A Strunnikov, SMC proteins and chromosome structure Trends in Cell Biology. ,vol. 8, pp. 454- 459 ,(1998) , 10.1016/S0962-8924(98)01370-1
Paul E. Perry, Induction of sister-chromatid exchanges (SCEs) by thymidine and the potentiation of mutagen-induced SCEs in Chinese hamster ovary cells Mutation Research. ,vol. 109, pp. 219- 229 ,(1983) , 10.1016/0027-5107(83)90048-9
K. Kimura, Phosphorylation and Activation of 13S Condensin by Cdc2 in Vitro Science. ,vol. 282, pp. 487- 490 ,(1998) , 10.1126/SCIENCE.282.5388.487