ANTI-HER2 NANOBODY AND CODING SEQUENCE AND USE THEREOF

作者: Wong Chung Lim , Ting Hong Hoi , Huang Wenhua

DOI:

关键词:

摘要: Provided are an anti-Her2 nanobody and a coding sequence the use thereof. In particular, provided is combating human epidermal growth factor receptor-2 (Her2/ERBB2). Disclosed gene encoding nanobody, corresponding expression vector host cell capable of expressing method for producing present invention related The may also provide immunoconjugate thereof, especially in diagnosis treatment Her2 positive tumor.

参考文章(5)
Arvind Chopra, [99mTc]Epidermal growth factor receptor–specific nanobody National Center for Biotechnology Information (US). ,(2008)
Hendricus Renerus Jacobus Mattheus Hoogenboom, Carlo Boutton, Hilde Adi Pierrette Revets, Amino acid sequences directed against her2 and polypeptides comprising the same for the treatment of cancers and/or tumors ,(2008)
Tom Maniatis, Joseph Sambrook, E. F. Fritsch, Molecular Cloning: A Laboratory Manual ,(2001)
Xu Genxing, Zhu Haowen, Rong Zhigang, Gu Peng, Huang Peihua, Hua Zichun, Recombinant human endostatin fusion protein as well as preparation method and application thereof ,(2017)
Li Hongli, Zhuang Wenchao, Ling Zhi, Anti-Her2 nano antibody ,(2017)