Congenital Rubella Syndrome Surveillance as a Platform for Surveillance of Other Congenital Infections, Peru, 2004–2007

作者: Alvaro Whittembury , Jorge Galdos , María Lugo , Luis Suárez-Ognio , Ana Ortiz

DOI: 10.1093/INFDIS/JIR407

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摘要: BACKGROUND Rubella during pregnancy can cause serious fetal abnormalities and death. Peru has had integrated measles/rubella surveillance since 2000 but did not implement congenital rubella syndrome (CRS) until 2004, in accordance with the Pan American Health Organization recommendations for elimination. The article describes experience from CRS sentinel system Peru. METHODS maintained a national reporting confirmed suspected cases 2004. A protocol was implemented standardized case definitions instruments selected sites. Each site completes their investigations report forms sends reports to Region Epidemiology Department, which forwards data Department. were analyzed period 2004-2007. RESULTS During 2004-2007, 16 health facilities, are located 9 of 33 regions, representing 3 main geographical areas (coast, mountain, jungle), included as sites surveillance. total 2061 reported system. Of these, 11 classified 23 infection. Factors significantly associated vertical transmission were: (1) mother, maternal history rash (odds ratio [OR], 12.0; 95% confidence interval [CI], 3.8-37.8); (2) infant, pigmentary retinopathy (OR, 18.4; CI, 3.2-104.6), purpura 14.7; 2.8-78.3), developmental delay 4.4; 1.75-11.1). CONCLUSIONS been able identify transmission, reinforcing evidence that public problem This may serve platform other infections

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