Intestinal Perfusion Methods for Oral Drug Absorptions

Yoshihiro Tanaka, Yoko Taki, Toshiyasu Sakane, Tanekazu Nadai, Hitoshi Sezaki, Shinji Yamashita, Characterization of drug transport through tight-junctional pathway in Caco-2 monolayer: comparison with isolated rat jejunum and colon. Pharmaceutical Research. ,vol. 12, pp. 523- 528 ,(1995) , 10.1023/A:1016245711557

Yukiya Hashimoto, Hiroaki Sasa, Masahiro Shimomura, Ken‐ichi Inui, Effects of intestinal and hepatic metabolism on the bioavailability of tacrolimus in rats. Pharmaceutical Research. ,vol. 15, pp. 1609- 1613 ,(1998) , 10.1023/A:1011967519752

Ming Hu, Ronald T. Borchardt, MECHANISM OF L-ALPHA -METHYLDOPA TRANSPORT THROUGH A MONOLAYER OF POLARIZED HUMAN INTESTINAL EPITHELIAL CELLS (CACO-2) Pharmaceutical Research. ,vol. 7, pp. 1313- 1319 ,(1990) , 10.1023/A:1015906409585

Patrick J. Sinko, Peidi Hu, Determining Intestinal Metabolism and Permeability for Several Compounds in Rats. Implications on Regional Bioavailability in Humans Pharmaceutical Research. ,vol. 13, pp. 108- 113 ,(1996) , 10.1023/A:1016041620024

Patrick J. Sinko, Gordon L. Amidon, Characterization of the Oral Absorption of β-Lactam Antibiotics. I. Cephalosporins: Determination of Intrinsic Membrane Absorption Parameters in the Rat Intestine In Situ Pharmaceutical Research. ,vol. 5, pp. 645- 650 ,(1988) , 10.1023/A:1015974920682

Marie‐Catherine Grès, Bernard Julian, Martine Bourrié, Viviane Meunier, Claude Roques, Marion Berger, Xavier Boulenc, Yves Berger, Gérard Fabre, Correlation between oral drug absorption in humans, and apparent drug permeability in TC-7 cells, a human epithelial intestinal cell line : Comparison with the parental Caco-2 cell line Pharmaceutical Research. ,vol. 15, pp. 726- 733 ,(1998) , 10.1023/A:1011919003030

Hilde Bohets, Pieter Annaert, Geert Mannens, Ludy van Beijsterveldt, Katelijne Anciaux, Peter Verboven, Willem Meuldermans, Karel Lavrijsen, Strategies for Absorption Screening in Drug Discovery and Development Current Topics in Medicinal Chemistry. ,vol. 1, pp. 367- 383 ,(2001) , 10.2174/1568026013394886

Staffan Tavelin, Jan Taipalensuu, Finn Hallböök, Kati-Sisko Vellonen, Vanessa Moore, Per Artursson, None, An improved cell culture model based on 2/4/A1 cell monolayers for studies of intestinal drug transport: characterization of transport routes. Pharmaceutical Research. ,vol. 20, pp. 373- 381 ,(2003) , 10.1023/A:1022643802296

Urban Fagerholm, Monica Johansson, Hans Lennernäs, Comparison between permeability coefficients in rat and human jejunum. Pharmaceutical Research. ,vol. 13, pp. 1336- 1342 ,(1996) , 10.1023/A:1016065715308

Hans Lennernäs, Örjan Ahrenstedt, Roger Hällgren, Lars Knutson, Märta Ryde, Lennart K. Paalzow, Regional rectal perfusion: a new in vivo approach to study rectal drug absorption in man. Pharmaceutical Research. ,vol. 12, pp. 426- 432 ,(1995) , 10.1023/A:1015888813741