Statistical Methods for Detecting Selective Sweeps

摘要: The emigration of humankind from Africa and the adoption agriculture have meant that selective pressures on changed in recent evolutionary times. A sweep occurs when a positive mutation spreads through population. For example, enables adults to digest lactase has spread Northern European population, although it is very rare African Since neutral alleles are strongly linked such also tend these sweeps leave signature, valley low genetic variation.This article reviews development statistical tests for detection using genomic data, particularly light advances genome mapping. It points out directions future research.