The Essential Role of Calcium Phosphate Bioceramics in Bone Regeneration

摘要: Various bioceramics or xenograft has been used to avoid autograft. However, there are large differences in the chemistry, micro- and macrostructure, consequently performance terms of resorption, absorption, regeneration physiological bone. The such available were reported critical data presented. Recent developments related CaP scaffolds including improvements engineering surface properties, microstructure, porosities, which lead them be considered as being bioinstructive rather than osteoconductive scaffolds, have opened up new opportunities for bone regenerative technologies. Not only some these osteoinductive their own right, but evidence also supports hypothesis that specific a direct influence on differentiation proliferation human mesenchymal stem cells (hMSCs). Tissue engineering, bioactive molecules, surgical technologies increase potential application carriers capable guiding behavior efficiency regeneration. If smart scaffold technology led higher efficacy it would allow further applications tissue mechanical properties required ingrowth remodeling mechanotransduction must explored development generation scaffolds.