The cell biology of receptor-mediated virus entry.

作者: Joe Grove , Mark Marsh

DOI: 10.1083/JCB.201108131

关键词:

摘要: The cell imposes multiple barriers to virus entry. However, viruses exploit fundamental cellular processes gain entry cells and deliver their genetic cargo. Virus pathways are largely defined by the interactions between particles receptors at surface. These determine mechanisms of attachment, uptake, intracellular trafficking, and, ultimately, penetration cytosol. Elucidating complex interplay is necessary for a full understanding how these remarkable agents invade hosts.

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