Green synthesis and immobilization of TiO2 NPs using ILs-based on imidazole and investigation of its catalytic activity for the efficient synthesis of pyrimido[4,5-d]pyrimidines

摘要: Abstract In this study pyrimido[4,5-d]pyrimidine derivatives have been synthesized via a suitable and efficient procedure using one-pot multi-component reactions of phenylisocyanate, N,N-dimethyl-6-amino uracil aromatic aldehydes in presence TiO2@ILs as nanocatalyst. method all products were prepared with good to excellent yields TiO2@ILs. Moreover, TiO2 NPs beet juice extract functionalized ILs based on imidazole. nanocatalyst has characterized by different spectroscopic techniques such FT-IR, TGA, XRD, SEM EDX. ionic liquid presented itself protective activator agent for nanocatalysts.