Sedentary Death Syndrome

摘要: Sedentary death syndrome (SeDS) is a major public health burden due to its causing multiple chronic diseases and millions of premature deaths each year. Despite the impact physical inactivity, very little known about actual causes inactivity-induced diseases. It important study mechanisms underlying molecular changes related inactivity in order better understand scientific basis individualized exercise prescription therapies for diseases, support improved efforts by providing proof that an cause Physical activity has genetic basis. A subpopulation genes, which have functioned survival through most humankind's existence, require daily maintain long-term vitality. Type 2 diabetes (T2D) example SeDS condition, as it almost entirely preventable with activity. To determine true role development progression T2D, information presented indicates comparisons should be made physically active controls, rather than sedentary this population healthiest. Use subjects control group led potentially misleading interpretations. If individuals were designated group, different interpretation would been drawn. thought there no difference GLUT4 concentration between T2D groups. However, expression higher controls Therefore, obtain causal allow scientifically based prevention therapy strategies, must serve group.