From biomarkers to therapeutic targets—the promises and perils of long non-coding RNAs in cancer

Shihong Cao, Weiliang Liu, Feng Li, Weipin Zhao, Chuan Qin, Decreased expression of lncRNA GAS5 predicts a poor prognosis in cervical cancer International Journal of Clinical and Experimental Pathology. ,vol. 7, pp. 6776- 6783 ,(2014)

Rui-Jun Li, Xing-Hua Li, Jia-Zhuan Mei, Zhi-Quan Tu, Down-regulation of long non-coding RNA GAS5 is associated with the prognosis of hepatocellular carcinoma. International Journal of Clinical and Experimental Pathology. ,vol. 7, pp. 4303- 4309 ,(2014)

Shinichi Nakagawa, Lessons from reverse-genetic studies of lncRNAs. Biochimica et Biophysica Acta. ,vol. 1859, pp. 177- 183 ,(2016) , 10.1016/J.BBAGRM.2015.06.011

Jun-Qing Hou, Wen-Chao Xu, Xiao-Lei Zhao, Zhen-Hua Zhao, Xin-Yi Du, Increased expression of SPRY4-IT1 predicts poor prognosis and promotes tumor growth and metastasis in bladder cancer International Journal of Clinical and Experimental Pathology. ,vol. 8, pp. 1954- 1960 ,(2015)

Qingyu Shi, Guangwen Zhang, Da Pang, Zilong You, Nanxia Bai, Shiyao Sui, Song Gao, Chao Zhan, Jinfeng Zhang, Shouping Xu, Feng Liu, Downregulation of long noncoding RNA MALAT1 induces epithelial-to-mesenchymal transition via the PI3K-AKT pathway in breast cancer International Journal of Clinical and Experimental Pathology. ,vol. 8, pp. 4881- 4891 ,(2015)

Dumitrascu T, Badea L, Dima So, Popescu I, Herlea, Combined gene expression analysis of whole-tissue and microdissected pancreatic ductal adenocarcinoma identifies genes specifically overexpressed in tumor epithelia. Hepato-gastroenterology. ,vol. 55, pp. 2016- 2027 ,(2008)

Jian-Ping Che, Yang Yan, Jun-Hua Zheng, Hai-Min Zhang, Feng-Qiang Yang, High expression of long non-coding RNA SPRY4-IT1 predicts poor prognosis of clear cell renal cell carcinoma. International Journal of Clinical and Experimental Pathology. ,vol. 7, pp. 5801- 5809 ,(2014)

Ahmad Salameh, Alessandro K. Lee, Marina Cardó-Vila, Diana N. Nunes, Eleni Efstathiou, Fernanda I. Staquicini, Andrey S. Dobroff, Serena Marchiò, Nora M. Navone, Hitomi Hosoya, Richard C. Lauer, Sijin Wen, Carolina C. Salmeron, Anh Hoang, Irene Newsham, Leandro A. Lima, Dirce M. Carraro, Salvatore Oliviero, Mikhail G. Kolonin, Richard L. Sidman, Kim-Anh Do, Patricia Troncoso, Christopher J. Logothetis, Ricardo R. Brentani, George A. Calin, Webster K. Cavenee, Emmanuel Dias-Neto, Renata Pasqualini, Wadih Arap, PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3 Proceedings of the National Academy of Sciences of the United States of America. ,vol. 112, pp. 8403- 8408 ,(2015) , 10.1073/PNAS.1507882112

Mark Pickard, Gwyn Williams, Molecular and Cellular Mechanisms of Action of Tumour Suppressor GAS5 LncRNA. Genes. ,vol. 6, pp. 484- 499 ,(2015) , 10.3390/GENES6030484

M. Peter Marinkovich, Laminin 332 in squamous-cell carcinoma Nature Reviews Cancer. ,vol. 7, pp. 370- 380 ,(2007) , 10.1038/NRC2089