BDNF-TrkB receptor regulation of distributed adult neural plasticity, memory formation, and psychiatric disorders.
作者： Raül Andero , Dennis C. Choi , Kerry J. Ressler
DOI: 10.1016/B978-0-12-420170-5.00006-4
关键词:
摘要: Brain-derived neurotrophic factor (BDNF) and its single transmembrane receptor, tropomysin-related kinase B (TrkB), are essential for adult synaptic plasticity the formation of memories. However, there regional task-dependent differences underlying differential mechanisms BDNF-TrkB function in these Additionally, BDNF pathway has been implicated several psychiatric disorders including posttraumatic stress disorder, phobia, panic disorder. Gaining a better understanding this neurobiology memory through fundamental research may be helpful to identify effective prevention treatment approaches both diseases deficit as well cases enhanced aversive memory, such anxiety disorders.
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