τ in Paired Helical Filaments Is Functionally Distinct from Fetal τ: Assembly Incompetence of Paired Helical Filament‐τ
作者： Hirotaka Yoshida , Yasuo Ihara
DOI: 10.1111/J.1471-4159.1993.TB03642.X
关键词:
摘要: tau in paired helical filaments (PHF-tau) and fetal share several phosphorylated epitopes, as revealed by phosphorylation-dependent PHF monoclonals. We have asked whether there is any difference between the two molecules tubulin assembly-promoting activity found that PHF-tau almost assembly incompetent, whereas low this but still competent. This indicates despite substantial similarities immunoreactivities, are quite distinct from each other function.
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