A highly sensitive microfluidics system for multiplexed surface-enhanced Raman scattering (SERS) detection based on Ag nanodot arrays
作者： Gang Chen , Yuyang Wang , Hailong Wang , Ming Cong , Lei Chen
DOI: 10.1039/C4RA09251A
关键词:
摘要: We report a method for fabricating highly sensitive, microfluidic surface-enhanced Raman scattering (SERS) chip with ordered Ag nanodot arrays as the enhancement substrate detection of multiplexed low-concentration analytes. The SERS features highly-ordered array on quartz slides fabricated by depositing an ultrathin anodic aluminium oxide (AAO) film template and channel-patterned polydimethylsiloxane (PDMS) cover top, allowing tremendous electromagnetic field in proximity surface because localized plasmon resonance (LSPR) nanodots. Via utilization self-built microspectrometer inverted configuration, signals low concentration adenine thiram can be readily detected limit down to 5.0 × 10−7 M. This system that we developed is flexible has potential real commercialization.
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