The role of dendritic cell precursors in tumour vasculogenesis

作者: G Coukos , F Benencia , R J Buckanovich , J R Conejo-Garcia

DOI: 10.1038/SJ.BJC.6602476

关键词:

摘要: In this review, we discuss the recent identification in vivo of a population CD11c+ cells exhibiting simultaneous expression both endothelial and dendritic cell markers, termed vascular leukocytes (VLCs). VLCs are highly represented human ovarian carcinomas and, depending on milieu, can assemble into functional blood vessels or act as antigen-presenting cells. The precursors bipotent has important implications for physiopathology therapy tumours. emerge novel therapeutic target against tumour vascularisation.

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