Naloxone distribution and possession following a large‐scale naloxone programme

摘要: Aims To examine uptake following a large-scale naloxone programme by estimating distribution rates since initiation and the proportion among sample of high-risk individuals who had attended training, currently possessed or used naloxone. We also estimated likelihood possession use as function duration, individual descriptive substance indicators. Design (1) Distribution data (June 2014-August 2017) date implementation for each city (2) cross-sectional study illicit users interviewed September 2017. Setting Seven Norwegian cities. Participants A total 497 recruited illegal opioids and/or central stimulants. Measurements Primary outcomes: use. Random-intercepts logistic regression models (covariates: male, age, homelessness/shelter use, overdose, incarceration, opioid maintenance treatment, income sources, indicators, duration). Findings Overall, 4631 nasal sprays were distributed in two pilot cities, with cumulative rate 495 per 100 000 population. In same individuals, 44% 62% reported current possession. The corresponded well to duration participating city's programme. six distributing 58% 43% 15% significant indicators [adjusted odds ratios (aOR) = 1.44, 95% confidence interval (CI 0.82-2.37], female gender (aOR 1.97, CI 1.20-3.24) drug-dealing 2.36, 1.42-3.93). 1.49 95%, 1.15-1.92), 2.06, 1.02-4.17), treatment (OMT) 2.07, 1.13-3.78), 2.40, 1.27-4.54) heroin injecting 2.13, 1.04-4.38). Conclusions seven cities population indicated good saturation an important indicator