A hemodynamic study of atrial septal defect and associated anomalies involving the atrial septum

摘要: Abstract An interatrial communication was found as a significant lesion in total of 121 patients studied up to 1954 the cardiac catheterization laboratory Mayo Clinic. Of these patients, 44 were considered be examples uncomplicated atrial septal defect, 13 had associated pulmonary hypertension, 6 anomalous connection one or more veins, persistent common atrioventricular canals, and 2 mitral valve disease. The hemodynamic data obtained from 71 form basis for this report. In without hypertension blood flow greatly increased (average 8.3 L./min./M. ) due presence left-toright shunting considerable degree. number it demonstrated that shunted left right, greater proportion originated right lung than lung. Small right-to-left shunts significance shown exist frequently, inferior caval superior origin. systemic normal. majority with severe flows reduced magnitude. large calculated. Patients veins canal may show same fundamental circulatory disorder an defect usual type. frequency practical importance each lesions are compelling reasons they sought diagnosed preoperatively. Highly suggestive evidence critical analysis oxygen saturation separate series samples drawn different locations ventricle, atrium both venae cavae. Differences some magnitude between at random sites, but placed on difference is consistently demonstrated. A correlation pressure gradient across frequently flow. did not appear pathologically degree stenosis.