L-carnitine administration in coronary artery disease and cardiomyopathy.

摘要: Myocardial ischaemia may be defined as a deficiency in cardiac energy supply relative to demand. In coronary artery disease (CAD), oxygen is limited due obstruction so production not enough meet the demands for work. Several reports involving about 2500 patients of CAD where carnitine was administered upto 1 year indicate some beneficial effects. There reduction showing reduced ST-segment depression and angina, greater effort tolerance decreased need drugs. Carnitine can cause overall improvement performance with well cardiomyopathy. More studies are necessary demonstrate scavenge free radicals apart from its effect on fatty acid metabolism. Side effects mild nausea vomiting dose 2 g/day 3 divided doses have any side Intravenous L-carnitine acts rapidly has no