Curcumin immune-mediated and anti-apoptotic mechanisms protect against renal ischemia/reperfusion and distant organ induced injuries.
作者： Azza S. Awad , Amany A. El-Sharif
DOI: 10.1016/J.INTIMP.2011.02.015
关键词:
摘要: Abstract Renal ischemia followed by reperfusion results in kidney injury which turn produces and releases destructive inflammatory cytokines into the circulation causing subsequent distant organ injury. Little data suggest immune mechanism of curcumin on protection against ischemia/reperfusion induced We investigated immunomodulatory anti-apoptotic effects (I/R) rats. Thirty-six rats were randomly divided three experimental groups (sham, I/R pretreated I/R, n = 12 each). Curcumin was administered orally to group. can significantly decrease both systemic as well blood levels (p
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