Pulmonary arterial hypertension: an update on diagnosis and treatment.
作者： Nipa R. Shah , Richard Stringham
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摘要: Pulmonary arterial hypertension is defined as a mean pulmonary pressure greater than 25 mm Hg at rest or 30 during physical activity. classified into subgroups, including idiopathic, heritable, and associated with other conditions. A detailed history, thorough examination, most importantly, high index of suspicion are essential to diagnosis. Evaluation includes echocardiography exclusion causes symptoms. Targeted laboratory testing can help identify the subgroup hypertension. Right heart catheterization required confirm Standard treatment options include oral anticoagulation, diuretics, oxygen supplementation, for small percentage patients, calcium channel blockers. Newer treatments prostacyclin analogues, endothelin receptor antagonists, phosphodiesterase type 5 inhibitors. Combination therapy has been shown improve pressure, but more research needed. Interventional procedures patients balloon atrial septostomy lung transplantation.
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