Displacement of brain regions in preterm infants with non-synostotic dolichocephaly investigated by MRI.

摘要: Regional investigations of newborn MRI are important to understand the appearance and consequences early brain injury. Previously, regionalization in neonates has been achieved with a Talairach parcellation, using internal landmarks brain. Non-synostotic dolichocephaly defines bi-temporal narrowing preterm infant's head caused by pressure on immature skull. The impact shape regional shift, which may compromise validity parcellation scheme, not yet investigated. Twenty-four 20 fullterm infants were scanned at term equivalent. Skull shapes investigated cephalometric measurements population registration. Brain tissue volumes calculated rule out injury underlying skull differences. position was evaluated. Cortical structures segmented determine positional shift between both groups. group displayed dolichocephalic had similar compared mesocephalic group. In infants, consistently positioned relative each other base, but displaced regard calvarium. frontal superior region enlarged; central temporal gyri sulci shifted comparing infants. We found that, healthy led cortical structures, did influence deep structures. concluded that scheme is compromised lead miscalculation inconsistent parcel contents when infant populations divergent shapes.