Imaging of seasonal affective disorder and seasonality effects on serotonin and dopamine function in the human brain.

摘要: According to current knowledge, disturbances in brain monoamine transmission play a major role many psychiatric disorders, and of the radioligands used for investigating these disorders bind targets within systems. However, phylogenetically ancient prevailing function monoamines is mediate adaptation organisms cells rhythmical changes light conditions, other environmental rhythms, such as temperature, or availability energy resources throughout seasons. The physiological systems mediating are highly conserved species, including humans. Here we review literature on seasonal binding monoaminergic ligands human brain. Moreover, argue importance considering possible effects season when healthy subjects with disorders.