Osteomyelitis Therapy – General Considerations and Surgical Therapy

作者: Marc Baltensperger , Gerold Eyrich

DOI: 10.1007/978-3-540-28766-7_8

关键词:

摘要: The final common pathway in all treatment of acute and secondary chronic osteomyelitis the jaws is to achieve a shift disturbed balance between responsible pathogen(s) host defenses latter, allowing body overcome infection. Reduction pathogens achieved by surgical removal infected necrotic tissue as well antibiotic therapy. Improvement local vascularization further accomplished decortication, exceeding conventional debridement, which not only removes poorly vascularized (infected) bone but also brings well-vascularized affected bone, thus facilitating healing process antibiotics reach target area; therefore, surgery are be considered major columns treating jaws. Hyperbaric oxygen (HBO), can recognized an adjunctive therapeutic modality osteomyelitis, supports host-defensive mechanisms promotes has direct toxic effects on microorganisms causing Although never dominating therapy, HBO third column armentarium for treatment. A sufficient debridement most important factor successful advanced extent dictated mainly bone. procedure addition bring well-perfused contact with site decortication procedure, workhorse main goal primary jawbone cessation or amelioration symptoms. In addition, deformity may must surgically addressed. Dealing symptoms, aside from surgery, several conservative options available. Even though disease been cured, change course severity should sign success.

参考文章(27)
Tatsumi Sugata, Yoshinori Fujita, Yoshinari Myoken, Takeshi Kiriyama, Successful management of severe facial pain in patients with diffuse sclerosing osteomyelitis (DSO) of the mandible using disodium clodronate. International Journal of Oral and Maxillofacial Surgery. ,vol. 32, pp. 574- 575 ,(2003) , 10.1016/S0901-5027(03)90401-7
Gerold K Eyrich, Marc M. Baltensperger, Robert E. Marx, Osteomyelitis Of The Jaws ,(2009)
James R. Hupp, [edited by] Richard G. Topazian, Morton H. Goldberg, Oral and Maxillofacial Infections ,(1987)
Marjut Montonen, Tateyuki Iizuka, Dorrit Hallikainen, Christian Lindqvist, Decortication in the treatment of diffuse sclerosing osteomyelitis of the mandible. Retrospective analysis of 41 cases between 1969 and 1990. Oral Surgery, Oral Medicine, Oral Pathology. ,vol. 75, pp. 5- 11 ,(1993) , 10.1016/0030-4220(93)90397-M
Alan M Rosenberg, Paul Babyn, Ronald M Laxer, Sandrine Compeyrot-Lacassagne, Pamidronate treatment of chronic noninfectious inflammatory lesions of the mandible in children. The Journal of Rheumatology. ,vol. 34, pp. 1585- 1589 ,(2007)
Stanisław B. Bartkowski, Piotr B. Heczko, Jerzy Lisiewicz, Jerzy Dorożyński, Marian Kurek, Józef Kuśmiderski, Józef Kasprzyk, Combined treatment with antibiotic, heparin and streptokinase--a new approach to the therapy of bacterial osteomyelitis. Journal of Cranio-maxillofacial Surgery. ,vol. 22, pp. 167- 176 ,(1994) , 10.1016/S1010-5182(05)80384-1
G. K. H. Eyrich, C. Harder, H. F. Sailer, T. Langenegger, E. Bruder, B. A. Michel, Primary chronic osteomyelitis associated with synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO syndrome). Journal of Oral Pathology & Medicine. ,vol. 28, pp. 456- 464 ,(2007) , 10.1111/J.1600-0714.1999.TB02106.X
Robert E. Marx, Osteoradionecrosis: A new concept of its pathophysiology Journal of Oral and Maxillofacial Surgery. ,vol. 41, pp. 283- 288 ,(1983) , 10.1016/0278-2391(83)90294-X
Brian Alpert, Theresa Colosi, J.A. von Fraunhofer, David Seligson, The In Vivo Behavior of Gentamicin-PMMA Beads in the Maxillofacial Region Journal of Oral and Maxillofacial Surgery. ,vol. 47, pp. 46- 49 ,(1989) , 10.1016/0278-2391(89)90123-7
John W. Hellstein, Cindy L. Marek, Bisphosphonate Osteochemonecrosis (Bis-Phossy Jaw): Is This Phossy Jaw of the 21st Century? Journal of Oral and Maxillofacial Surgery. ,vol. 63, pp. 682- 689 ,(2005) , 10.1016/J.JOMS.2005.01.010