Concentration of urine in a central core model of the renal counterflow system
作者： John L. Stephenson
DOI: 10.1038/KI.1972.75
关键词:
摘要: Concentration of urine in a central core model the renal counterflow system. In this descending Henle's limbs (DHL), ascending (AHL) and collecting ducts (CD) exchange with vascular (VC) formed by vasa recta loops—assumed so highly permeable that functions as single tube, open at cortical end closed papillary end. Solute supplied to VC primarily AHL increases osmolality extracts water from DHL CD, increasing their while diluting fluid. This effect multiplied arrangement leads high all structures. Some solute may enter be recycled. system energy requirements for transport out decrease outer inner medulla. two systems (e.g. salt urea) mixing can supply part final concentration urine. Urea cycling, regulated ADH, allows active Na + medulla cortex used
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