Challenges and Opportunities of Centrifugal Microfluidics for Extreme Point-of-Care Testing

作者: Issac Michael , Tae-Hyeong Kim , Vijaya Sunkara , Yoon-Kyoung Cho

DOI: 10.3390/MI7020032

关键词:

摘要: The advantages offered by centrifugal microfluidic systems have encouraged its rapid adaptation in the fields of vitro diagnostics, clinical chemistry, immunoassays, and nucleic acid tests. Centrifugal devices are currently used both point-of-care settings. Recent studies shown that this new diagnostic platform could be potentially extreme settings like remote villages Indian subcontinent Africa. Several technological inventions decentralized diagnostics developing countries; however, very few technologies been successful meeting demand. By identifying finest difference between testing infrastructure, review captures evolving needs countries paired with infrastructural challenges hurdles to healthcare delivery In particular, requirements for making viable discussed based on a detailed analysis demands different including distinctive

参考文章(46)
Suzanne Smith, Kevin Land, Marc Madou, Horacio Kido, RAPID, LOW-COST PROTOTYPING OF CENTRIFUGAL MICROFLUIDIC DEVICES FOR EFFECTIVE IMPLEMENTATION OF VARIOUS MICROFLUIDIC COMPONENTS † South African Journal of Industrial Engineering. ,vol. 26, pp. 179- 190 ,(2015) , 10.7166/26-1-944
Brandon L Thompson, Yiwen Ouyang, Gabriela R M Duarte, Emanuel Carrilho, Shannon T Krauss, James P Landers, Inexpensive, rapid prototyping of microfluidic devices using overhead transparencies and a laser print, cut and laminate fabrication method Nature Protocols. ,vol. 10, pp. 875- 886 ,(2015) , 10.1038/NPROT.2015.051
Anthony K. Mbonye, Pascal Magnussen, Sham Lal, Kristian S. Hansen, Bonnie Cundill, Clare Chandler, Siân E. Clarke, A Cluster Randomised Trial Introducing Rapid Diagnostic Tests into Registered Drug Shops in Uganda: Impact on Appropriate Treatment of Malaria PLOS ONE. ,vol. 10, pp. e0129545- ,(2015) , 10.1371/JOURNAL.PONE.0129545
Price Cp, St John A, Existing and Emerging Technologies for Point-of-Care Testing. The Clinical biochemist. Reviews / Australian Association of Clinical Biochemists. ,vol. 35, pp. 155- 167 ,(2014)
David Mabey, Rosanna W. Peeling, Andrew Ustianowski, Mark D. Perkins, Diagnostics for the developing world. Nature Reviews Microbiology. ,vol. 2, pp. 231- 240 ,(2004) , 10.1038/NRMICRO841
Mara Jana Broadhurst, John Daniel Kelly, Ann Miller, Amanda Semper, Daniel Bailey, Elisabetta Groppelli, Andrew Simpson, Tim Brooks, Susan Hula, Wilfred Nyoni, Alhaji B Sankoh, Santigi Kanu, Alhaji Jalloh, Quy Ton, Nicholas Sarchet, Peter George, Mark D Perkins, Betsy Wonderly, Megan Murray, Nira R Pollock, ReEBOV Antigen Rapid Test kit for point-of-care and laboratory-based testing for Ebola virus disease: a field validation study The Lancet. ,vol. 386, pp. 867- 874 ,(2015) , 10.1016/S0140-6736(15)61042-X
S. Hawkes, K. White, H. Kettler, Mapping the landscape of diagnostics for sexually transmitted infections: key findings and recommendations. Mapping the landscape of diagnostics for sexually transmitted infections: key findings and recommendations.. ,(2004)
Marc J. Madou, Gregory J. Kellogg, LabCD: a centrifuge-based microfluidic platform for diagnostics Systems and Technologies for Clinical Diagnostics and Drug Discovery. ,vol. 3259, pp. 80- 93 ,(1998) , 10.1117/12.307314
Allyson V. Ritchie, Ines Ushiro-Lumb, Daniel Edemaga, Hrishikesh A. Joshi, Annemiek De Ruiter, Elisabeth Szumilin, Isabelle Jendrulek, Megan McGuire, Neha Goel, Pia I. Sharma, Jean-Pierre Allain, Helen H. Lee, SAMBA HIV Semiquantitative Test, a New Point-of-Care Viral-Load-Monitoring Assay for Resource-Limited Settings Journal of Clinical Microbiology. ,vol. 52, pp. 3377- 3383 ,(2014) , 10.1128/JCM.00593-14