Non-azo naphthalimide dyes and uses for same

作者: Ronald E. Utecht , David E. Lewis , J. Lester Matthews , Millard M. Judy

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摘要: A class of predominantly hydrophobic non-azo N-substituted 1,8-naphthalimide compounds, each bearing, at its 3-position, a nucleofuge and, 4-position, heteroatomic electron-releasing group. The group is being characterized as having heteroatom directly linked to the 4-position ring, and least one hydrogen attached heteroatom. Upon activation by an activating agent in environment independent presence or absence oxygen, these compounds generate activated species. species initiate chemical changes lipid bilayer membranes viruses other target cells. These can eradicate also cause structural any associated proteins polypeptides level beneath surface membrane, leading polymerization crosslinking.

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