Both low muscle mass and low fat are associated with higher all-cause mortality in hemodialysis patients.

作者: Cindy X. Huang , Hocine Tighiouart , Srinivasan Beddhu , Alfred K. Cheung , Johanna T. Dwyer

DOI: 10.1038/KI.2009.524

关键词:

摘要: A higher body mass index is associated with better outcomes in hemodialysis patients; however, this does not differentiate between fat and muscle mass. In order to clarify this, we examined the relationship measures of mortality 1709 patients from Hemodialysis Study. Triceps skin-fold thickness was used assess mid-arm circumference Cox regression evaluate composition all-cause after adjustments for demographic, cardiovascular, dialysis, nutrition-related risk factors. During a median follow-up 2.5 years, there were 802 deaths. adjusted models continuous covariates, triceps significantly decreased hazards mortality, while showed trend toward mortality. models, lower quartiles thickness, circumference, all These studies show that end-stage renal disease bears complex

参考文章(40)
Rosalind S. Gibson, Nutritional assessment: a laboratory manual Oxford University Press. ,(1993)
William E. Siri, Body composition from fluid spaces and density: analysis of methods. 1961 Nutrition. ,vol. 9, pp. 480- 492 ,(1993)
ED Harlow, David Lane, A Laboratory manual Cold Spring Harbor Laboratory. ,(1989)
Jae-Hyung Chang, Vladimir Mushailov, Sumit Mohan, None, Obesity and Kidney Transplantation Contributions To Nephrology. ,vol. 151, pp. 19- 41 ,(2006) , 10.1159/000095317
Kamyar Kalantar-Zadeh, Kevin C Abbott, Abdulla K Salahudeen, Ryan D Kilpatrick, Tamara B Horwich, Survival advantages of obesity in dialysis patients The American Journal of Clinical Nutrition. ,vol. 81, pp. 543- 554 ,(2005) , 10.1093/AJCN/81.3.543
SF Leavey, RL Strawderman, CA Jones, FK Port, PJ Held, Simple nutritional indicators as independent predictors of mortality in hemodialysis patients. American Journal of Kidney Diseases. ,vol. 31, pp. 997- 1006 ,(1998) , 10.1053/AJKD.1998.V31.PM9631845
Harold Bays, Lawrence Blonde, Robert Rosenson, Adiposopathy: how do diet, exercise and weight loss drug therapies improve metabolic disease in overweight patients? Expert Review of Cardiovascular Therapy. ,vol. 4, pp. 871- 895 ,(2006) , 10.1586/14779072.4.6.871
R. Kakiya, T. Shoji, Y. Tsujimoto, N. Tatsumi, S. Hatsuda, K. Shinohara, E. Kimoto, H. Tahara, H. Koyama, M. Emoto, E. Ishimura, T. Miki, T. Tabata, Y. Nishizawa, Body fat mass and lean mass as predictors of survival in hemodialysis patients Kidney International. ,vol. 70, pp. 549- 556 ,(2006) , 10.1038/SJ.KI.5000331
Essam F. Elsayed, Hocine Tighiouart, Daniel E. Weiner, John Griffith, Deeb Salem, Andrew S. Levey, Mark J. Sarnak, Waist-to-Hip Ratio and Body Mass Index as Risk Factors for Cardiovascular Events in CKD American Journal of Kidney Diseases. ,vol. 52, pp. 49- 57 ,(2008) , 10.1053/J.AJKD.2008.04.002
Doris I. Stenver, Anders Gotfredsern, Jannik Hilsted, Bent Nielsen, Body Composition in Hemodialysis Patients Measured by Dual-Energy X-Ray Absorptiometry American Journal of Nephrology. ,vol. 15, pp. 105- 110 ,(1995) , 10.1159/000168812