作者: Johannes W. Tack , Renate Heithecker , Michael Huempel , Juergen Hilman , Ralph Lipp
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摘要: A pharmaceutical composition comprises, as a first active agent, 6β,7β;15β,16β-dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone (drospirenone) in an amount corresponding to daily dosage, on administration of the composition, from about 2 mg 4 mg, and, second 17α-ethinylestradiol (ethinylestradiol) dosage 0.01 0.05 together with one or more pharmaceutically acceptable carriers excipients. In specific embodiment, consists number separately packaged and individually removable units placed packaging unit intended for oral period at least 21 consecutive days, wherein said comprises combination drospirenone ethinylestradiol. The may further comprise 7 less containing no agent ethinylestradiol alone.