Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics

作者: Ferdinand Brandl , Fritz Kastner , Ruth M. Gschwind , Torsten Blunk , Jörg Teßmar

DOI: 10.1016/J.JCONREL.2009.10.030

关键词:

摘要: … Hydrogels have been studied as injectable drug delivery … favorable characteristics, these drug delivery systems still have not … One reason is that the quantity and homogeneity of drug …

参考文章(33)
Tom K. L. Meyvis, Stefaan C. De Smedt, Patrick Van Oostveldt, Joseph Demeester, Fluorescence recovery after photobleaching: a versatile tool for mobility and interaction measurements in pharmaceutical research. Pharmaceutical Research. ,vol. 16, pp. 1153- 1162 ,(1999) , 10.1023/A:1011924909138
Paul J. Flory, Principles of polymer chemistry ,(1953)
James C. Bray, Edward W. Merrill, Poly(vinyl alcohol) hydrogels. Formation by electron beam irradiation of aqueous solutions and subsequent crystallization Journal of Applied Polymer Science. ,vol. 17, pp. 3779- 3794 ,(1973) , 10.1002/APP.1973.070171219
Yves Gnanou, Gerard Hild, Paul Rempp, Molecular structure and elastic behavior of poly(ethylene oxide) networks swollen to equilibrium Macromolecules. ,vol. 20, pp. 1662- 1671 ,(1987) , 10.1021/MA00173A037
C. Guse, S. Koennings, F. Kreye, F. Siepmann, A. Goepferich, J. Siepmann, Drug release from lipid-based implants: Elucidation of the underlying mass transport mechanisms International Journal of Pharmaceutics. ,vol. 314, pp. 137- 144 ,(2006) , 10.1016/J.IJPHARM.2005.08.030
Vijay S. Sukumar, Stephanie T. Lopina, Network model for the swelling properties of end-linked linear and star poly(ethylene oxide) hydrogels Macromolecules. ,vol. 35, pp. 10189- 10192 ,(2002) , 10.1021/MA0213753
Juergen Siepmann, Nicholas Peppas, Florence Siepmann, Mathematical modeling of drug delivery. International Journal of Pharmaceutics. ,vol. 364, pp. 328- 343 ,(2008) , 10.1016/J.IJPHARM.2008.09.004
G.P. Raeber, M.P. Lutolf, J.A. Hubbell, Molecularly Engineered PEG Hydrogels: A Novel Model System for Proteolytically Mediated Cell Migration Biophysical Journal. ,vol. 89, pp. 1374- 1388 ,(2005) , 10.1529/BIOPHYSJ.104.050682
Alma J. Kuijpers, Gerard H. M. Engbers, Tom K. L. Meyvis, Stefaan S. C. de Smedt, Joseph Demeester, Jeroen Krijgsveld, Sebastian A. J. Zaat, Jacob Dankert, Jan Feijen, Combined Gelatin−Chondroitin Sulfate Hydrogels for Controlled Release of Cationic Antibacterial Proteins Macromolecules. ,vol. 33, pp. 3705- 3713 ,(2000) , 10.1021/MA9917702