Short communication: High prevalence of transmitted antiretroviral drug resistance among newly HIV type 1 diagnosed adults in Mombasa, Kenya
作者： Kim C.E. Sigaloff , Kishor Mandaliya , Raph L. Hamers , Francis Otieno , Irene M. Jao
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摘要: Abstract In view of the recent antiretroviral therapy (ART) scale-up in Kenya, surveillance transmitted HIV drug resistance (TDR) is important. A cross-sectional survey was conducted among newly HIV-1 diagnosed, antiretroviral-naive adults Mombasa, Kenya. Surveillance mutations (SDRMs) were identified according to 2009 WHO list. subtypes determined using REGA and SCUEAL subtyping tools. Genotypic test results obtained for 68 81 participants, SDRMs 9 samples. Resistance nonnucleoside reverse transcriptase inhibitors (K103N) occurred five yielding a TDR prevalence 7.4% (95% confidence interval 2.4–16.3%). Frequencies (70.6%), C (5.9%), D (2.9%), unique recombinant forms (20.6%). The found this higher than previously reported different regions These findings justify increased vigilance with respect African where ART pro...
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