Antibiotic treatment of patients with mucosal thickening in the paranasal sinuses, and validation of cut-off points in sinus CT.

摘要: We compared the efficacy of penicillin V and amoxycillin treatment with placebo in 70 adult patients from Norwegian family practice a clinical diagnosis acute sinusitis mucosal thickening on CT, but without fluid level or total opacification. The study was randomized double-blind. Three different outcomes were evaluated; subjective status after 10 days treatment, difference score between day 0 10, duration illness episode. Amoxycillin gave no better response to than placebo, evaluated by all three outcome measures. median episode amoxycillin- groups 13 penicillin-V group. In sinusitis, opacification CT are good criteria differentiate that need do not antibiotic treatment.