Multiple Effects Cost-Effectiveness Analysis in Cost-Disutility Space

摘要: Chapter 10 shows that the net benefit correspondence theorem methods, introduced and shown to have distinct advantages for multiple strategy comparisons in Chap. 8 provider efficiency comparison consistent with maximising 9, naturally extend such robust domain under uncertainty. In 4 we highlighted generalisable methods enable jointly considering costs effects uncertainty are required better inform funding decisions complex clinical areas as palliative care. While quality-adjusted life years (QALYs) integration of patient survival morbidity, they either unable, or struggle, incorporate domains carer impacts, family distress, finalising personal financial affairs being community choice place care death. Consequently, without cost-effectiveness analysis, use conventional single outcome evaluation (QALY measures otherwise) can misrepresent key preferences. Scarce resources funds easily end up supporting interventions, strategies programmes overall negative impacts not options maximise outcomes from limited resources. this chapter show how analysis cost-disutility (CDU) space enables joint consideration facilitating improved societal decision making. We outline illustrate (NBCT) on CDU plane also facilitate effect analogous summary measures. New identify across any set threshold values lowest expected loss (ENL) highest ENL planes potential value undertaking further research optimal contour well probability having (CEA planes).