Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity.
作者： Sylvie Lachkar , Laura Senovilla , Lorenzo Galluzzi , Oliver Kepp , Gérard Pierron
DOI: 10.1016/J.MOLCEL.2012.09.013
关键词:
摘要: … which STAT3 regulates autophagy. Our results indicate that cytoplasmic STAT3 tonically suppresses autophagy … of eIF2α, which is required for autophagy induction by multiple stimuli. …
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sci-hub.se 参考文章(54)
Richard Jove, Michelle A. Blaskovich, Jiazhi Sun, Saïd M. Sebti, Alan Cantor, James Turkson, Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice. Cancer Research. ,vol. 63, pp. 1270- 1279 ,(2003)
David E. Levy, J. E. Darnell, STATs: transcriptional control and biological impact Nature Reviews Molecular Cell Biology. ,vol. 3, pp. 651- 662 ,(2002) , 10.1038/NRM909
Alfredo Criollo, Mireia Niso-Santano, Shoaib Ahmad Malik, Mickael Michaud, Eugenia Morselli, Guillermo Mariño, Sylvie Lachkar, Alexander V Arkhipenko, Francis Harper, Gérard Pierron, Jean-Christophe Rain, Jun Ninomiya-Tsuji, José M Fuentes, Sergio Lavandero, Lorenzo Galluzzi, Maria Chiara Maiuri, Guido Kroemer, Inhibition of autophagy by TAB2 and TAB3 The EMBO Journal. ,vol. 30, pp. 4908- 4920 ,(2011) , 10.1038/EMBOJ.2011.413
Rachel Cooney, John Baker, Oliver Brain, Benedicte Danis, Tica Pichulik, Philip Allan, David JP Ferguson, Barry J Campbell, Derek Jewell, Alison Simmons, None, NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nature Medicine. ,vol. 16, pp. 90- 97 ,(2010) , 10.1038/NM.2069
Sophie Pattingre, Amina Tassa, Xueping Qu, Rita Garuti, Xiao Huan Liang, Noboru Mizushima, Milton Packer, Michael D. Schneider, Beth Levine, Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy Cell. ,vol. 122, pp. 927- 939 ,(2005) , 10.1016/J.CELL.2005.07.002
Eugenia Morselli, Lorenzo Galluzzi, Oliver Kepp, Guillermo Mariño, Mickael Michaud, Ilio Vitale, Maria Chiara Maiuri, Guido Kroemer, Oncosuppressive functions of autophagy. Antioxidants & Redox Signaling. ,vol. 14, pp. 2251- 2269 ,(2011) , 10.1089/ARS.2010.3478
Alfredo Criollo, Laura Senovilla, Hélène Authier, Maria Chiara Maiuri, Eugenia Morselli, Ilio Vitale, Oliver Kepp, Ezgi Tasdemir, Lorenzo Galluzzi, Shensi Shen, Maximilien Tailler, Nicolas Delahaye, Antoine Tesniere, Daniela De Stefano, Aména Ben Younes, Francis Harper, Gérard Pierron, Sergio Lavandero, Laurence Zitvogel, Alain Israel, Véronique Baud, Guido Kroemer, The IKK complex contributes to the induction of autophagy The EMBO Journal. ,vol. 29, pp. 619- 631 ,(2010) , 10.1038/EMBOJ.2009.364
D. R. Green, L. Galluzzi, G. Kroemer, Mitochondria and the autophagy-inflammation-cell death axis in organismal aging Science. ,vol. 333, pp. 1109- 1112 ,(2011) , 10.1126/SCIENCE.1201940
Anthony Orvedahl, Diane Alexander, Zsolt Tallóczy, Qihua Sun, Yongjie Wei, Wei Zhang, Dennis Burns, David A. Leib, Beth Levine, HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. Cell Host & Microbe. ,vol. 1, pp. 23- 35 ,(2007) , 10.1016/J.CHOM.2006.12.001
Eugenia Morselli, Shensi Shen, Christoph Ruckenstuhl, Maria Anna Bauer, Guillermo Mariño, Lorenzo Galluzzi, Alfredo Criollo, Mickael Michaud, Maria Chiara Maiuri, Tokuhiro Chano, Frank Madeo, Guido Kroemer, None, p53 inhibits autophagy by interacting with the human ortholog of yeast Atg17, RB1CC1/FIP200. Cell Cycle. ,vol. 10, pp. 2763- 2769 ,(2011) , 10.4161/CC.10.16.16868