Mucociliary Clearance and Mucus Secretion in the Lung

摘要: The drainage of the nose, sinuses, and bronchial tree is accomplished by essentially same biomechanical principles — mucociliary clearance mechanism. Described originally in nose (Yates 1924), sinuses (Hilding 1932), bronchi 1957) as “ciliary streaming”, airways are considered to have an overlying, continuous mucous blanket that dimensionally thin, but has a high viscosity so it sustains limited traction. Under motivation ciliary action, mucus moves sheet nasal passages from larynx, passing over posterior margin pharynx. Areas lacking cilia thought be cleared traction surrounding ciliated areas.