Discovery of a novel Shp2 protein tyrosine phosphatase inhibitor
作者： Liwei Chen , Shen-Shu Sung , M. L. Richard Yip , Harshani R. Lawrence , Yuan Ren
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摘要: … by a Gab1-Shp2 chimera but did not affect the Shp2-… Shp2 PTP in cell cultures without a detectable off-target effect. Our study also provides the first pharmacological evidence that Shp2 …
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