Formation of seven- and eight-membered rings by manganese (III)-based oxidative free radical cyclization.
作者： John E. Merritt , Marvin Sasson , Steven A. Kates , Barry B. Snider
DOI: 10.1016/S0040-4039(00)80718-2
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摘要: Abstract Oxidative free-radical cyclizations of acetoacetates 1 , 8 17 and 20 with Mn(OAc) 3 ·2H 2 Cu(OAc) ·H O in acetic acid provide cycloheptenes cyclooctenes moderate to good yield. Tandem 28 35 51 bicyclo[4.2.1]nonanes, bicyclo[5.2.1]decanes, bicyclo[5.3.0]decanes bicyclo[6.3.0]undecanes.
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