Identification, isolation and elimination of cancer stem cells
作者： Laurie Ailles , Irving L. Weissman , Catriona Helen M. Jamieson
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摘要: Isolated populations of leukemic stem cells are provided. The useful for experimental evaluation, and as a source lineage cell specific products, targets the discovery factors or molecules that can affect them. Detection is in predicting disease progression, relapse, development drug resistance. Proliferation LSC may be inhibited through interfering with activation bcatenin pathway. Methods provided clinical staging pre-leukemia leukemias by differential analysis hematologic samples distribution one more hematopoietic progenitor subsets.
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