Novel Therapeutic Strategy Using Interventional Radiology (IVR) for Hepatitis C Virus (HCV)-Related Decompensated Liver Cirrhosis: A Case Report.

摘要: BACKGROUND The appearance of direct acting antivirals (DAAs) has produced a major paradigm shift in hepatitis C virus (HCV) infection treatment, and elimination become possible most patients. Improvement the model for end-stage liver disease (MELD) score by HCV been reported, but decompensated cirrhosis, it is also important to overcome various complications before antiviral treatment. CASE REPORT A 72-year-old male, who had treated HCV-related cirrhosis was referred our hospital treatment refractory hepatic encephalopathy. At that time, his Child-Pugh 10 class C. On contrast-enhanced computed tomography (CT), splenorenal shunt, splenomegaly, splenic artery aneurysm were noted. complicated cytopenia associated with hypersplenism, embolization partial (PSE) concomitantly performed. One month after PSE, balloon occluded retrograde transvenous obliteration (BRTO) encephalopathy Hepatic functional reserve improved compared at first examination, SOF/LDV therapy initiated. Fortunately, no adverse effect occurred during sustained virologic response (SVR) achieved. further thereafter. time this report, status being maintained without administration branched chain amino acid preparation, drugs hyperammonemia, or diuretics. CONCLUSIONS We encountered patient accompanied encephalopathy, aneurysm. These PSE BRTO, which led DAAs marked improvement function.