摘要: Although oral nonsteroidal anti-inflammatory drugs (NSAIDs) are effective in the treatment of a variety acute and chronic pain conditions, their use may be associated with serious systemic adverse effects, particularly gastrointestinal disorders. In order to minimise incidence events related such agents, topical NSAIDs have been developed. Topical NSAIDs, applied as gels, creams or sprays, penetrate skin, subcutaneous fatty tissue muscle amounts that sufficient exert therapeutic effect on peripheral central mechanisms absence high plasma concentrations. Data indicate at relieving number indications.