作者: Elena V. Stashina , Nikolay A. Gavrilov , Petr D. Shabanov
DOI: 10.17816/RCF1535-21
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摘要: Environmental toxicants, chemicals exhibiting with cholinotropics properties, and drugs – agonists antagonists of M- N-cholinergic receptors by acting on the developing brain fetus in embryonic period ontogenesis, cause a change activity cholinergic mechanisms during critical periods prenatal development subsequent disruption formation different systems, primarily ontogeny nerve cells neurotransmitter systems. These changes long term is correlated neurobehavioral deficits from adult individuals, dysfunction reproductive system offspring. The relevance study effects factors central function, memory processes learning ontogenetic organism due to need prevention treatment mental, behavioral, sexual dysfunctions, abnormal behavior, infertility.