Kidney Function and Injury After Nephrectomy for Kidney Cancer

摘要: Radical nephrectomy (RN) is an established standard in the treatment of renal cell cancer. Surgical innovation has focused on preservation residual function by way partial (PN) selected patients while reducing surgical invasiveness and preserving oncological efficacy. Yet, 25 % undergoing kidney cancer surgery experience immediate postoperative complications, risk higher with preoperative chronic disease (CKD). Key intraoperative factors injury include warm/cold ischemia, blood loss, effects pneumoperitoneum, rhabdomyolysis, direct loss nephron mass. Current standards biochemical assessment are suboptimal, as they do not allow remnant function. Renal scintigraphic techniques may provide one method assessing differential damage to each kidney, tissue-specific biomarkers ischemic offer hope add diagnostic prognostic value current methods.