Screening for heart disease in diabetic subjects

摘要: Background The prevalence of left ventricular hypertrophy (LVH), coronary artery disease, and subclinical cardiomyopathy in diabetic patients without known cardiac disease is unclear. We sought the frequency these findings to determine whether plasma brain natriuretic peptide (BNP) could be used as an alternative screening tool identify LV dysfunction. Methods Asymptomatic with diabetes mellitus (n = 101) underwent clinical evaluation, measurement BNP, exercise stress testing, detailed echocardiographic assessment. After exclusion overt dysfunction or ischemia, myocardial function was on basis systolic (Sm) diastolic velocity (Em). Association between clinical, biochemical, exercise, variables. Results Of 101 patients, 22 had LVH 16 ischemia evidenced by exercise-induced wall motion abnormalities. Only 4 abnormal BNP levels; significantly increased LVH. identified 24 66 patients. Subclinical not predicted BNP. Conclusions Even after asymptomatic hypertrophy, occurs a significant number type 2 diabetes. However, approaches, including do appear sufficiently sensitive dysfunction, which requires sophisticated analysis.