Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs.
作者： Stephanie Heinzlmeir , Denis Kudlinzki , Sridhar Sreeramulu , Susan Klaeger , Santosh Lakshmi Gande
DOI: 10.1021/ACSCHEMBIO.6B00709
关键词:
摘要: … small molecule kinase inhibitors. We identified 24 submicromolar EPHA2 inhibitors in this way and … in complex with EPHA2 to determine the structural basis for kinase inhibition. The …
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